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8-OH-Dpat

Catalog No. T4305   CAS 78950-78-4
Synonyms: 8-Hydroxy-DPAT

8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.

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8-OH-Dpat Chemical Structure
8-OH-Dpat, CAS 78950-78-4
Pack Size Availability Price/USD Quantity
5 mg In stock $ 39.00
10 mg In stock $ 55.00
25 mg In stock $ 113.00
50 mg In stock $ 178.00
100 mg In stock $ 271.00
1 mL * 10 mM (in DMSO) In stock $ 48.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
Targets&IC50 5-HT1A:pIC50 = 8.19, 5-HT7:
Synonyms 8-Hydroxy-DPAT
Molecular Weight 247.38
Formula C16H25NO
CAS No. 78950-78-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 49 mg/mL (198.07 mM)

TargetMolReferences and Literature

1. Bard JA, et al. Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase. J Biol Chem. 1993 Nov 5;268(31):23422-6. 2. DEREK N. MIDDLEMISS, et al. 8-HYDROXY-2-(DI-n-PROPYLAMINO)-TETRALIN DISCRIMINATES BETWEEN SUBTYPES OF 3. Mori T, et al. Narcolepsy-like sleep disturbance in orexin knockout mice are normalized by the 5-HT1A receptor agonist 8-OH-DPAT. Psychopharmacology (Berl). 2016 Jun;233(12):2343-53.

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Keywords

8-OH-Dpat 78950-78-4 GPCR/G Protein Neuroscience 5-HT Receptor 5-hydroxytryptamine Receptor Serotonin Receptor inhibit 8OHDpat 8 OH Dpat Inhibitor 8-Hydroxy-DPAT inhibitor

 

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