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8-​Prenylnaringenin

Catalog No. TN1146   CAS 53846-50-7
Synonyms: 8-Prenylnaringenin

8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
8-​Prenylnaringenin Chemical Structure
8-​Prenylnaringenin, CAS 53846-50-7
Pack Size Availability Price/USD Quantity
1 mg In stock $ 186.00
5 mg In stock $ 460.00
10 mg In stock $ 676.00
25 mg In stock $ 1,060.00
50 mg In stock $ 1,430.00
100 mg In stock $ 1,930.00
1 mL * 10 mM (in DMSO) In stock $ 470.00
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Purity: 99.67%
Purity: 99.46%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,
In vitro In vitro, aggregates of buccal epithelial cells were irradiated and cultured in suspension for 11 days. 8-PN or TAM were investigated regarding their effect on cell shedding. In vivo, the lower tongue surface of mice was irradiated with graded single doses of 25 kV X-rays. The incidence, latency, and duration of the resulting mucosal ulcerations were analyzed after topical treatment with 8-PN, TAM or solvent. 8-PN or TAM prevented the volume reduction of the irradiated cell aggregates during the incubation period. This was the result of a higher residual cell number in the treated versus the untreated irradiated aggregates. In vivo, topical treatment with 8-PN or TAM significantly increased the latency of mucositis from 10.9 to 12.1 and 12.4 days respectively, while the ulcer incidence was unchanged[1]
Source
Synonyms 8-Prenylnaringenin
Molecular Weight 340.37
Formula C20H20O5
CAS No. 53846-50-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 22.5 mg/mL (66.1 mM)

TargetMolReferences and Literature

1. 8-prenylnaringenin and tamoxifen inhibit the shedding of irradiated epithelial cells and increase the latency period of radiation-induced oral mucositis : cell culture and murine model.Strahlenther Onkol. 2015 May;191(5):429-36.

Related compound libraries

This product is contained In the following compound libraries：
Anti-Cancer Active Compound Library Miao medicine Compound Library Traditional Chinese Medicine Monomer Library Cuproptosis Compound Library NF-κB Signaling Compound Library Flavonoid Natural Product Library Anti-Aging Compound Library Natural Product Library Lipid Metabolism Compound Library Bioactive Compounds Library Max

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Millepachine EGFR-IN-12 GSK2801 Liensinine Perchlorate Ac-DEVD-CHO Liensinine Dinaciclib TCS JNK 5a

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Keywords

8-​Prenylnaringenin 53846-50-7 Apoptosis Immunology/Inflammation ROS inhibit 8​Prenylnaringenin 8-Prenylnaringenin 8-?Prenylnaringenin Inhibitor 8 ​Prenylnaringenin inhibitor

 

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