Powder: -20°C for 3 years | In solvent: -80°C for 1 year
A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 133.00 | |
2 mg | In stock | $ 197.00 | |
5 mg | In stock | $ 297.00 | |
10 mg | In stock | $ 453.00 | |
25 mg | In stock | $ 747.00 | |
50 mg | In stock | $ 1,050.00 | |
100 mg | In stock | $ 1,420.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 312.00 |
Description | A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist |
Targets&IC50 | TRPV1:3-9 nM |
In vivo | systemic administration of the TRPV1 antagonist, A-425619, reversed the decrease in digging behavior induced by CFA injection, further confirming the role of TRPV1, expressed by knee neurons, in acute inflammatory joint pain. |
Synonyms | 1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA |
Molecular Weight | 345.32 |
Formula | C18H14F3N3O |
CAS No. | 581809-67-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 34.5 mg/mL (100 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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A 425619 581809-67-8 Membrane transporter/Ion channel TRP/TRPV Channel A425619 1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA A-425619 inhibitor inhibit