Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ACP-105 is a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 38.00 | |
2 mg | In stock | $ 54.00 | |
5 mg | In stock | $ 89.00 | |
10 mg | In stock | $ 139.00 | |
25 mg | In stock | $ 278.00 | |
50 mg | In stock | $ 396.00 | |
100 mg | In stock | $ 572.00 | |
500 mg | In stock | $ 1,190.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 98.00 |
Description | ACP-105 is a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone. |
Targets&IC50 | AR (T877A):9.3 (pEC50), AR (WT):9.0 (pEC50) |
In vitro | ACP-105 is an orally administered, selective, and potent androgen receptor modulator (SARM), demonstrating high affinity with pEC50 values of 9.0 and 9.3 for the AR wild type and T877A mutant, respectively. In human hepatocytes, the half-life of ACP-105 (compound 1) is determined to be 5.0 hours[1]. |
In vivo | Irradiation impaired sensorimotor function in vehicle-treated mice but not in ACP-105-treated mice. Irradiation impaired cued fear conditioning and ACP-105 enhanced fear conditioning in sham-irradiated and irradiated mice. There are relatively early radiation-induced behavioral changes in female mice and reduced MAP-2 levels in the sensorimotor cortex following ACP-105 treatment might contribute to enhanced rotorod performance[2]. |
Molecular Weight | 290.79 |
Formula | C16H19ClN2O |
CAS No. | 899821-23-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (206.33 mM)
Ethanol: 60 mg/mL(206.33 mM)
You can also refer to dose conversion for different animals. More
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ACP-105 899821-23-9 Endocrinology/Hormones Androgen Receptor ACP 105 inhibit ACP105 Inhibitor inhibitor