store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AG-825(Tyrphostin C15) is a selective and competitive ErbB2 inhibitor that inhibits tyrosine phosphorylation with an IC50 value of 0.35 μM.AG-825 (Tyrphostin C15) inhibits HER2 and shows anticancer activity in a mouse xenograft model of breast cancer.AG-825 ( Tyrphostin C15) is a potentially active molecule for overcoming manganese-induced neurotoxicity or the development of Alzheimer's disease, and promotes apoptosis in human neutrophils, which could be used in the study of breast cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 30.00 | |
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 113.00 | |
25 mg | In stock | $ 247.00 | |
50 mg | In stock | $ 413.00 | |
100 mg | In stock | $ 663.00 | |
500 mg | In stock | $ 1,370.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | AG-825(Tyrphostin C15) is a selective and competitive ErbB2 inhibitor that inhibits tyrosine phosphorylation with an IC50 value of 0.35 μM.AG-825 (Tyrphostin C15) inhibits HER2 and shows anticancer activity in a mouse xenograft model of breast cancer.AG-825 ( Tyrphostin C15) is a potentially active molecule for overcoming manganese-induced neurotoxicity or the development of Alzheimer's disease, and promotes apoptosis in human neutrophils, which could be used in the study of breast cancer. |
Targets&IC50 | EGFR:19 μM, ErbB2:0.35 μM |
Synonyms | Tyrphostin AG-825 |
Molecular Weight | 397.47 |
Formula | C19H15N3O3S2 |
CAS No. | 149092-50-2 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 200 mg/mL (503.18 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AG-825 149092-50-2 Angiogenesis Apoptosis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR Tyrphostin AG825 AG825 Tyrphostin AG-825 AG 825 Tyrphostin AG 825 inhibitor inhibit