Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AGN 192836 is a potent and selective α2 adrenergic agonist (EC50s: 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,080.00 | |
50 mg | 8-10 weeks | $ 1,410.00 | |
100 mg | 8-10 weeks | $ 2,220.00 |
Description | AGN 192836 is a potent and selective α2 adrenergic agonist (EC50s: 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor). |
Targets&IC50 | α2A:(EC50)8.7 nM , α2B: 41 nM , α2C: 6.6 nM |
In vitro | AGN 192836 is 1200-fold selective for the α2A-receptor relative to the α1-receptor, 50-fold selective for the α2A-receptor relative to the α2B-receptor, and 10-fold selective for the α2Areceptor relative to the α2C-receptor. |
In vivo | AGN 192836 demonstrates equivalent efficacy to brimonidine in lowering intraocular pressure when topically applied to rabbits and surpasses brimonidine's effectiveness in reducing blood pressure through intravenous administration in monkeys. |
Molecular Weight | 231.25 |
Formula | C12H13N3O2 |
CAS No. | 171102-29-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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AGN 192836 171102-29-7 Others AGN192836 AGN-192836 inhibitor inhibit