Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat TRPV1, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 43.00 | |
10 mg | In stock | $ 56.00 | |
25 mg | In stock | $ 118.00 | |
50 mg | In stock | $ 215.00 | |
100 mg | In stock | $ 377.00 | |
500 mg | In stock | $ 883.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat TRPV1, respectively). |
Targets&IC50 | TRPV1 (rat):85.6 nM, TRPV1 (human):24.5 nM |
In vivo | In a rat model of inflammatory pain induced by intraplantar injection of complete Freund's adjuvant, 30-100 mg/kg AMG 9810 reverses thermal and mechanical hyperalgesia[3]. |
Molecular Weight | 337.41 |
Formula | C21H23NO3 |
CAS No. | 545395-94-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 33 mg/mL (97.80 mM)
You can also refer to dose conversion for different animals. More
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AMG9810 545395-94-6 Membrane transporter/Ion channel TRP/TRPV Channel Transient receptor potential channels inhibit Inhibitor AMG-9810 TRP Channel AMG 9810 inhibitor