Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ASP1126 is a selective and orally active sphingosine-1-phosphate (S1P) agonist (EC50s: 7.12 nM, 517 nM for hS1P1 and hS1P3).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,670.00 | |
50 mg | 6-8 weeks | $ 2,180.00 | |
100 mg | 6-8 weeks | $ 2,800.00 |
Description | ASP1126 is a selective and orally active sphingosine-1-phosphate (S1P) agonist (EC50s: 7.12 nM, 517 nM for hS1P1 and hS1P3). |
Targets&IC50 | S1P1 (human):(EC50)7.12 nM , S1P3 (human): 517 nM |
In vitro | ASP1126 decreases the number of peripheral lymphocytes, naive T cells, central memory T cells, and effector memory T cells in the peripheral blood. |
In vivo | ASP1126 (1 and 5 mg/kg, orally once daily for 14 days) significantly prolongs allograft survival. ASP1126 in combination with 0.02 mg/kg tacrolimus notably improves graft survival time. |
Molecular Weight | 581.93 |
Formula | C26H26ClF6NO5 |
CAS No. | 1228580-11-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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ASP1126 1228580-11-7 Others ASP 1126 ASP-1126 inhibitor inhibit