1
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6396 | (R)-(-)-Gossypol acetic acid | (-)-Gossypol acetic acid , AT-101 (acetic acid) , (R)-Gossypol acetic acid , AT101 , AT101 acetate | Autophagy , BCL |
(R)-(-)-Gossypol acetic acid (AT101 acetate) , the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID. Phase 2. |