Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 41.00 | |
50 mg | In stock | $ 66.00 | |
100 mg | In stock | $ 97.00 | |
200 mg | In stock | $ 145.00 |
Description | Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection. |
In vitro | adefovir is a potent inhibitor of DHBV replication that inhibits CCC DNA amplification but does not effectively prevent the formation of CCC DNA from incoming viral genomes[1]. |
Cell Research | The effect of adefovir on viral CCC DNA synthesis was examined with primary cultures of DHBV-infected fetal hepatocytes.?Adefovir was administered for six consecutive days starting one day before or four days after DHBV inoculation.?Dose-dependent inhibition of both virion release in culture supernatants and synthesis of intracellular viral DNA was observed[1]. |
Molecular Weight | 273.19 |
Formula | C8H12N5O4P |
CAS No. | 106941-25-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 2.5 mM
DMSO: Insoluble
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Adefovir 106941-25-7 DNA Damage/DNA Repair Microbiology/Virology Telomerase Reverse Transcriptase HBV PMEA diphosphate monophosphate GS-0393 herpesviruses antiviral adenosine GS 0393 transcriptase Hepatitis B virus Inhibitor reverse HIV GS0393 inhibit inhibitor