Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 37.00 | |
10 mg | In stock | $ 51.00 | |
25 mg | In stock | $ 77.00 | |
50 mg | In stock | $ 98.00 | |
100 mg | In stock | $ 163.00 | |
500 mg | In stock | $ 393.00 |
Description | Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM) |
Targets&IC50 | ALK:1.9 nM |
In vivo | Alectinib hydrochloride(CH5424802), a potent, selective, and orally available ALK inhibitor with a unique chemical scaffold, showing preferential antitumor activity against cancers with gene alterations of ALK, such as nonsmall cell lung cancer (NSCLC) cells expressing EML4-ALK fusion and anaplastic large-cell lymphoma (ALCL) cells expressing NPM-ALK fusion in vitro and in vivo |
Animal Research | Animal Model:SCID or nude mice bearing NCI-H2228 cells. Dosage:0.2 mg/kg, 0.6 mg/kg, 2 mg/kg, 6 mg/kg, 20 mg/kg. Administration:Oral administration; once daily; for 11 days |
Synonyms | CH5424802 (Hydrochloride), AF-802 (Hydrochloride), RO5424802 (Hydrochloride) |
Molecular Weight | 519.08 |
Formula | C30H35ClN4O2 |
CAS No. | 1256589-74-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6 mg/mL (11.56 mM), sonification/heating is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Alectinib hydrochloride 1256589-74-8 Angiogenesis Tyrosine Kinase/Adaptors ALK Cluster of differentiation 246 CH-5424802 RO 5424802 AF-802 Alectinib Hydrochloride inhibit Inhibitor CH5424802 (Hydrochloride) AF802 Alectinib RO5424802 RO-5424802 CH 5424802 ALK tyrosine kinase receptor AF-802 (Hydrochloride) RO5424802 (Hydrochloride) Anaplastic lymphoma kinase CD246 CH5424802 Anaplastic lymphoma kinase (ALK) AF 802 inhibitor