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Alizarin

Catalog No. T2949 CAS 72-48-0

Synonyms: Mordant Red 11, Anthraquinonic

Alizarin (Mordant Red 11), a red dye derived from the roots of plants of the madder genus, inhibits P450 isoform CYP1A1( IC50 = 6.2 μM), CYP1A2 (IC50 =10.0 μM )and CYP1B1(IC50 = 2.7 μM).

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Alizarin, CAS 72-48-0

Pack Size	Availability	Price/USD
500 mg	In stock	$ 46.00
1 g	In stock	$ 55.00
5 g	In stock	$ 73.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 98.14%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Alizarin (Mordant Red 11), a red dye derived from the roots of plants of the madder genus, inhibits P450 isoform CYP1A1( IC50 = 6.2 μM), CYP1A2 (IC50 =10.0 μM )and CYP1B1(IC50 = 2.7 μM).
Targets&IC50	CYP1A1:6.2 μM, CYP1A2:10.0 μM, CYP1B1:2.7 μM
In vitro	Within the bodies of poisoned animals, Alizarin has been shown to reduce the levels of hepatic mercapturic acid conjugates and serum alanine transaminase (ALT) levels.
In vivo	In rat liver microsomes, Alizarin can inhibit the oxidation of phenoxy radicals, superoxide anion radicals, and lipid peroxides.
Source	Natural Products > Rubiaceae > Rubia

Synonyms	Mordant Red 11, Anthraquinonic
Molecular Weight	240.21
Formula	C14H8O4
CAS No.	72-48-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45 mg/mL (187.3 mM)

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: < 1 mg/mL (insoluble or slightly soluble)

References and Literature

1. Takahashi E, et al. Mutat Res, 2002, 508(1-2), 147-156. 2. Zhang J, et al. J Nutr Environ Med, 1997, 7(2), 79-89.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Tumor Natural Product Library Selected Plant-Sourced Compound Library RO5 Drug-like Natural Product Library Anti-Aging Compound Library Target-Focused Phenotypic Screening Library Metabolism Compound Library Ferroptosis Compound Library ReFRAME Related Library Chinese Pharmacopoeia Natural Product Library Anti-Cancer Compound Library

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Keywords

Alizarin 72-48-0 Metabolism P450 Inhibitor inhibit Mordant Red 11 Anthraquinonic inhibitor

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