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Alosetron hydrochloride

Catalog No. T2525 CAS 122852-69-1

Synonyms: Lotronex, GR 68755C, GR 68755, GR 68755X

Alosetron hydrochloride (GR 68755) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system, particularly on enteric and nociceptive sensory neurons, thereby affecting the regulation of visceral pain, decreasing gastrointestinal contraction and motility, and decreasing gastrointestinal secretions.

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Alosetron hydrochloride Chemical Structure

Alosetron hydrochloride, CAS 122852-69-1

Pack Size	Availability	Price/USD
10 mg	In stock	$ 39.00
25 mg	In stock	$ 75.00
50 mg	In stock	$ 143.00
100 mg	In stock	$ 226.00
200 mg	In stock	$ 343.00

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Purity: 100%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Lotronex, GR 68755C, GR 68755, GR 68755X
Molecular Weight	330.81
Formula	C17H19ClN4O
CAS No.	122852-69-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 2.5 mM

References and Literature

1. Spiller, Robin C. From Current Opinion in Pharmacology (2011), 11(1), 68-74.

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Inhibitor Library Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Anti-Cancer Approved Drug Library Drug Repurposing Compound Library Anti-Neurodegenerative Disease Compound Library Clinical Compound Library NO PAINS Compound Library Neuronal Signaling Compound Library

Related Products

Related compounds with same targets

Olopatadine hydrochloride Metergoline Ansofaxine hydrochloride Eplivanserin pCPA methyl ester hydrochloride Ocaperidone Spiroxatrine 3-Hydroxy agomelatine

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Alosetron hydrochloride 122852-69-1 GPCR/G Protein Neuroscience 5-HT Receptor Alosetron Hydrochloride Alosetron Lotronex selective depolarization Serotonin Receptor GR 68755C GR-68755 Inhibitor GR 68755 5-hydroxytryptamine Receptor GR68755 colitis nociceptive visceral inhibit GR 68755X inhibitor

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