Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 51.00 | |
200 mg | In stock | $ 90.00 | |
500 mg | In stock | $ 185.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity. |
In vitro | In elevated plus-maze and light/dark tests in BALB/c mice, Flumazenil (1 mg/kg) exhibited strong anxiolytic effects. Flumazenil (3 mg/kg) prevented alterations induced by chronic ethanol withdrawal in mice, such as decreased open arm time and percentage of open arm entries. In rats, Flumazenil (10 mg/kg) effectively counteracted the reductive effects of tetrahydropregnanolone. Flumazenil (5-20 mg/kg) antagonized the effects of diazepam in mice without affecting the anticonvulsant and adverse responses to GYKI52466. In the MES model, as opposed to the PTZ test, Flumazenil slightly reduced the anticonvulsant activity of NBQX. Flumazenil binds to central benzodiazepine (BZD) receptors, thereby antagonizing or reversing the neurophysiological effects of BZD depressants and agonists. It reverses the depressant sedative responses caused by the combined use of BZD and other drugs but is not effective for cyclic antidepressant overdose. |
Synonyms | Hexamethylmelamine, NSC13875, RB-1515, ENT-50852, WR-95704 |
Molecular Weight | 210.28 |
Formula | C9H18N6 |
CAS No. | 645-05-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12 mg/mL (57.1 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 8 mg/mL(38 mM)
You can also refer to dose conversion for different animals. More
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Altretamine 645-05-6 DNA Damage/DNA Repair DNA Alkylator/Crosslinker DNA Alkylation RB 1515 WR95704 Inhibitor WR 95704 inhibit Hexamethylmelamine ENT 50852 NSC13875 RB1515 NSC 13875 NSC-13875 ENT50852 RB-1515 ENT-50852 WR-95704 inhibitor