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Ampyrone

Catalog No. T0050   CAS 83-07-8
Synonyms: Minoazophene, Aminoantipyrin, NSC 60242, 4-Aminoantipyrine, Solnapyrin-A

Ampyrone (4-Aminoantipyrine) is a reagent for glucose determination in the presence of peroxidase and phenol.

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Ampyrone Chemical Structure
Ampyrone, CAS 83-07-8
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500 mg In stock $ 42.00
1 g In stock $ 50.00
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Purity: 100%
Purity: 98.57%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Ampyrone (4-Aminoantipyrine) is a reagent for glucose determination in the presence of peroxidase and phenol.
In vitro The level of glutathione(GSH) in single erythrocytes is impacted slightly at low AAP(4-aminoantipyrine) concentrations probably due to the protection of glutathione reductase. When AAP concentration further increases, AAP has a significant influence on GSH[2].
In vivo 4-aminoantipyrine (4-AA) is not genotoxic and mutagenic in vivo, it can interfere with DNA damaging agents biological activities and may reduce the effectiveness of DNA damage-based chemotherapy[3].
Cell Research Erythrocytes in PBS are incubated for 2 h at ambient temperature (without mixing) with AAP in concentrations from 1 × 10−6 mol/L to 1 × 10−3 mol/L. Sample of erythrocytes without AAP is used as control. After the exposure of AAP, erythrocytes are washed with borate buffer (pH 9.0) 2 times by centrifuging and determined for GSH. (Only for Reference)
Synonyms Minoazophene, Aminoantipyrin, NSC 60242, 4-Aminoantipyrine, Solnapyrin-A
Molecular Weight 203.24
Formula C11H13N3O
CAS No. 83-07-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 40 mg/mL (196.81 mM)

H2O: 37 mg/mL(182.1 mM)

TargetMolReferences and Literature

1. Vinagre AM, et al. Braz J Med Biol Res. 2016, 49(3). 2. Teng Y, et al. J Hazard Mater. 2011, 192(3):1766-1771. 3. Berno CR, et al. Mutat Res Genet Toxicol Environ Mutagen. 2016, 805:19-24.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Drug-Fragment Library Approved Drug Library Immunology/Inflammation Compound Library Neuronal Signaling Compound Library Anti-Cancer Compound Library Bioactive Compounds Library Max Bioactive Compound Library Nonsteroidal Anti-Inflammatory Compound Library

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Keywords

Ampyrone 83-07-8 Immunology/Inflammation Metabolism Neuroscience COX Drug Metabolite Inhibitor NSC60242 Minoazophene Aminoantipyrin Cyclooxygenase NSC 60242 inhibit 4-Aminoantipyrine Solnapyrin-A NSC-60242 inhibitor

 

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