Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 51.00 | |
2 mg | In stock | $ 74.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 178.00 | |
25 mg | In stock | $ 293.00 | |
50 mg | In stock | $ 413.00 | |
100 mg | In stock | $ 547.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 172.00 |
Description | Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization. |
In vitro | Ansamitocin p-3 inhibits the proliferation in a concentration-dependent manner with IC50s of 20, 50, 140, and 150 pM for MCF-7, HeLa, EMT-6/AR1, and MDA-MB-231 cells in culture, respectively. Ansamitocin P3 binds to purified tubulin (Kd = 1.3 µM)[1]. |
Synonyms | Maytansinol isobutyrate, Antibiotic C 15003P3, NSC292222 |
Molecular Weight | 635.14 |
Formula | C32H43ClN2O9 |
CAS No. | 66584-72-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (141.7 mM)
You can also refer to dose conversion for different animals. More
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Ansamitocin p-3 66584-72-3 Cytoskeletal Signaling Microtubule Associated Maytansinol isobutyrate NSC-292222 NSC 292222 Antibiotic C 15003P3 NSC292222 Maytansinol Isobutyrate inhibitor inhibit