Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Arazine (N-Acetyl-S-farnesyl-L-cysteine) can be a a substrate for isoprenylcysteine methyltransferase by competing with prenylated G protein or its receptors site. Arazine is a cell-permeable modulator of G protein and GPCR signaling.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 106.00 | |
25 mg | 6-8 weeks | Inquiry | |
50 mg | 6-8 weeks | Inquiry |
Description | Arazine (N-Acetyl-S-farnesyl-L-cysteine) can be a a substrate for isoprenylcysteine methyltransferase by competing with prenylated G protein or its receptors site. Arazine is a cell-permeable modulator of G protein and GPCR signaling. |
In vitro | Arazine (10–100 μM; 8h) significantly affects the HMEC-1 cell viability as measured by trypan blue exclusion in HMEC-1 cell. Arazine (2h) inhibits ATPγS induced CXCL1, CXCL8 and CCL2 production as a dose-dependent manner in HMEC-1 cell[2]. |
In vivo | Arazine (2,000 μg/20 μl) produces a dose-dependent inhibition of the TPA-induced edema, with the maximal reduction of edema approaching 73%, with an ED50 of 55 μg/20 μl[2]. |
Synonyms | N-Acetyl-S-farnesyl-L-cysteine |
Molecular Weight | 367.55 |
Formula | C20H33NO3S |
CAS No. | 135304-07-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Arazine 135304-07-3 Others inhibit cell-permeable substrate N-Acetyl-S-farnesyl-L-cysteine Inhibitor modulator inhibitor