Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic. Aripiprazole lauroxil is cleaved by esterases in vivo to N-hydroxymethyl aripiprazole (lauric acid), which is then cleaved to aripiprazole, which is non-toxic.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 41.00 | |
25 mg | In stock | $ 66.00 | |
50 mg | In stock | $ 97.00 | |
100 mg | In stock | $ 132.00 | |
200 mg | In stock | $ 198.00 | |
500 mg | In stock | $ 334.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic. Aripiprazole lauroxil is cleaved by esterases in vivo to N-hydroxymethyl aripiprazole (lauric acid), which is then cleaved to aripiprazole, which is non-toxic. |
In vivo | Intravenous administration of 1.87?mg/ml Aripiprazole lauroxil bioconversion in vivo involves the formation of an intermediate,?N-hydroxymethyl aripiprazole. The?in vitro?data indicates a high bioconversion of aripiprazole lauroxil, thus, the concentration of?N-hydroxymethyl aripiprazole observed in the animals dosed with aripiprazole lauroxil is surprisingly high[1]. |
Molecular Weight | 660.71 |
Formula | C36H51Cl2N3O4 |
CAS No. | 1259305-29-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8 mg/mL (12.11 mM)
You can also refer to dose conversion for different animals. More
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Aripiprazole Lauroxil 1259305-29-7 GPCR/G Protein Neuroscience 5-HT Receptor Dopamine Receptor schizophrenia Aristada inhibit Inhibitor inhibitor