Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Artemisone (BAY 44-9585) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains (IC50: 0.83 nM). It also is a potent inhibitor of human CMV.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 135.00 | |
5 mg | In stock | $ 289.00 | |
10 mg | In stock | $ 455.00 | |
25 mg | In stock | $ 753.00 | |
50 mg | In stock | $ 1,060.00 | |
100 mg | In stock | $ 1,430.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 318.00 |
Description | Artemisone (BAY 44-9585) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains (IC50: 0.83 nM). It also is a potent inhibitor of human CMV. |
Targets&IC50 | P. falciparum:0.83 nM |
In vitro | Artemisone inhibits 3D7 and K1 P. falciparum (IC50s: 0.88±0.59 and 1.23±0.64 nM). |
In vivo | Artemisone, when administered subcutaneously at doses of 3, 1, 0.3, and 0.1 mg/kg in conjunction with other antimalarials, demonstrates an enhanced effectiveness against the chloroquine-resistant P. yoelii NS strain[1]. Moreover, it is effective at inhibiting parasitemia in the P. berghei NY susceptible strain, achieving an ED50 of 9.62 mg/kg through the subcutaneous route and 11.67 mg/kg when given orally[1]. |
Synonyms | BAY 44-9585, Artemifone |
Molecular Weight | 401.52 |
Formula | C19H31NO6S |
CAS No. | 255730-18-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 130 mg/mL (323.77 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Artemisone 255730-18-8 Microbiology/Virology Others Parasite Cytomegalovirus Inhibitor BAY 44-9585 Artemifone CMV inhibit inhibitor