Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 3,020.00 | |
50 mg | 10-14 weeks | $ 3,980.00 | |
100 mg | 10-14 weeks | $ 5,500.00 |
Description | Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase). |
Targets&IC50 | Aurora A:4 nM, Aurora B:13 nM |
In vitro | Aurora inhibitor 1 (Compound 16) exhibits Kd values of 0.01?nM for both Aurora A and Aurora B kinase. |
In vivo | In vivo efficacy in a mouse xenograft tumor model when dosed orally, Aurora inhibitor 1 exhibits good drug exposure levels across species upon oral dosing and shows excellent. |
Molecular Weight | 459.57 |
Formula | C23H25N9S |
CAS No. | 2227019-45-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Aurora inhibitor 1 2227019-45-4 Cell Cycle/Checkpoint Chromatin/Epigenetic Aurora Kinase inhibitor inhibit