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Avanafil

Catalog No. T2334   CAS 330784-47-9
Synonyms: TA1790

Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.

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Avanafil Chemical Structure
Avanafil, CAS 330784-47-9
Pack Size Availability Price/USD Quantity
25 mg In stock $ 47.00
50 mg In stock $ 58.00
100 mg In stock $ 94.00
200 mg In stock $ 113.00
500 mg In stock $ 139.00
1 mL * 10 mM (in DMSO) In stock $ 50.00
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Purity: 99.66%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.
Targets&IC50 PDE5:1 nM
In vitro In the corpus cavernosum of rats with Type 2 Diabetes Mellitus (T2DM), the injection of Avanafil (1 μM) has been demonstrated to enhance erectile function.
Synonyms TA1790
Molecular Weight 483.95
Formula C23H26ClN7O3
CAS No. 330784-47-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 90 mg/mL (186 mM)

TargetMolReferences and Literature

1. Kotera J, et al. J Urol. 2012, 188(2), 668-674. 2. Yilmaz D, et al. Urology. 2014, 83(2), 508, e7-12.

Related compound libraries

This product is contained In the following compound libraries:
Highly Selective Inhibitor Library Anti-Neurodegenerative Disease Compound Library Approved Drug Library Drug-induced Liver Injury (DILI) Compound Library Bioactive Lipid Compound Library Target-Focused Phenotypic Screening Library Bioactive Compounds Library Max Clinical Compound Library Anti-Alzheimer's Disease Compound Library Anti-Metabolism Disease Compound Library

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Keywords

Avanafil 330784-47-9 Metabolism PDE Phosphodiesterase (PDE) bone density TA-1790 Endogenous Metabolite Inhibitor osteoporosis dexamethasone NOS Nitric oxide synthases corpus cavernosum erectile dysfunction inhibit NO Synthase TA 1790 TA1790 inhibitor

 

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