Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase ( DNA-PK ) inhibitor ( IC 50 =81 nM) which shows synergistic efficacy in combination with targeted alpha therapies. BAY-8400 can be used for the research of cancer [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 128.00 | |
5 mg | In stock | $ 263.00 | |
10 mg | In stock | $ 397.00 | |
25 mg | In stock | $ 813.00 | |
50 mg | In stock | $ 1,390.00 | |
100 mg | In stock | $ 1,880.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 288.00 |
Description | BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase ( DNA-PK ) inhibitor ( IC 50 =81 nM) which shows synergistic efficacy in combination with targeted alpha therapies. BAY-8400 can be used for the research of cancer [1]. |
Targets&IC50 | DNA-PK:81 nM |
In vivo | BAY-8400 (150 mg/kg; p.o.) increases the antitumor efficacy that even improved tumor-induced body weight loss. BAY-8400 shows useful aqueous solubility and oral bioavailability across species [1]. |
Molecular Weight | 393.39 |
Formula | C21H17F2N5O |
CAS No. | T9498 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (152.52 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BAY-8400 T9498 DNA Damage/DNA Repair PI3K/Akt/mTOR signaling DNA-PK BAY 8400 BAY8400 inhibitor inhibit