Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-survival activity against cancer cell lines with high BAZ1A expression, but weak or no activity against cancer cells with low BAZ1A expression.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 98.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 372.00 | |
25 mg | In stock | $ 629.00 | |
50 mg | In stock | $ 896.00 | |
100 mg | In stock | $ 1,220.00 | |
500 mg | In stock | $ 2,450.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 272.00 |
Description | BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-survival activity against cancer cell lines with high BAZ1A expression, but weak or no activity against cancer cells with low BAZ1A expression. |
Targets&IC50 | BAZ1A:0.52 μM(Kd), BAZ1A:5.08 μM (THP-1), 4.29 μM(ZR-75-30), 10.65 μM(BT474),7.70 μM(H1975 cells) |
In vitro | Administration of BAZ1A-IN-1 (0.015-100?μM; 96 hours) exhibits good anti-viability activity against all the four cancer cell lines that have a high expression level of BAZ1A, with IC50 values of 5.08 μM, 4.29 μM, 10.65 μM, and 7.70 μM for THP-1, ZR-75-30, BT474, and H1975 cells, respectively[1]. |
Molecular Weight | 340.36 |
Formula | C16H12N4O3S |
CAS No. | 941521-45-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (235.05 mM)
You can also refer to dose conversion for different animals. More
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BAZ1A-IN-1 941521-45-5 Chromatin/Epigenetic Epigenetic Reader Domain leukemia breast cancer BAZ1A IN 1 cancer ZR-75–30 BAZ1A BAZ1AIN1 THP-10 bromodomain-containing lung cancer H1975 inhibit BAZ-1A-IN-1 BT474 Inhibitor inhibitor