Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BCH001 is a specific small-molecule inhibitor of PAPD5.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 43.00 | |
10 mg | In stock | $ 72.00 | |
25 mg | In stock | $ 155.00 | |
50 mg | In stock | $ 288.00 | |
100 mg | In stock | $ 448.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | BCH001 is a specific small-molecule inhibitor of PAPD5. |
In vivo | BCH001, a specific PAPD5 inhibitor that restored telomerase activity and telomere length in DC patient induced pluripotent stem cells.?When human blood stem cells engineered to carry DC-causing PARN mutations were xenotransplanted into immunodeficient mice, oral treatment with a repurposed PAPD5 inhibitor, the dihydroquinolizinone RG7834, rescued TERC 3' end maturation and telomere length.? |
Molecular Weight | 420.34 |
Formula | C20H15F3N2O5 |
CAS No. | 384859-58-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 84 mg/mL (199.84 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BCH001 384859-58-9 Cell Cycle/Checkpoint DNA Damage/DNA Repair DNA/RNA Synthesis PARN dyskeratosis telomerase stem polynucleotide TERC rPAPD5 ncRNA BCH-001 polymerases oligo-adenylation congenita inhibit PAPD5 pluripotent BCH 001 iPSC telomere Inhibitor inhibitor