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BCX 1470

Catalog No. T13568 CAS 217099-43-9

BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.

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BCX 1470, CAS 217099-43-9

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description	BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.
Targets&IC50	Trypsin:326 nM , FD:96 nM , C1s:1.6 nM
In vitro	BCX 1470 is an inhibitor serine protease. BCX 1470 blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro.
In vivo	BCX 1470 blocked the development of RPA-induced edema in the rat.

Molecular Weight	302.37
Formula	C14H10N2O2S2
CAS No.	217099-43-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Szalai, Alexander J.; Digerness, Stanley B.; et al.; The Arthus Reaction in Rodents: Species-Specific Requirement of ComplementJournal of Immunology, 2000, 164, 463-468

Related Products

Related compounds with same targets

Nafamostat mesylate BMS-363131 BCX 1470 methanesulfonate PMSF BCX 1470 hydrochloride UK-371804 ZD8321 Aprotinin

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

BCX 1470 217099-43-9 Proteases/Proteasome Serine Protease BCX-1470 BCX1470 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.