Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 10-14 weeks | $ 376.00 | |
25 mg | 10-14 weeks | $ 1,140.00 | |
50 mg | 10-14 weeks | $ 1,490.00 | |
100 mg | 10-14 weeks | $ 2,360.00 |
Description | BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42). |
Targets&IC50 | β-Amyloid (1–42):ki: 6.4 nM |
In vitro | BF-168 is a potent agent that selectively recognizes SPs and NFTs in AD brain. BF-168 is a candidate probe for PET and is found to specifically recognize both neuritic and diffuse plaques. |
In vivo | Intravenous injection of BF-168 in PS1/APP and APP23 transgenic mice results in specific in vivo labeling to both compact and diffuse amyloid deposits in the brain. In addition, 18F-radiolabeled BF-168 demonstrates abundant initial brain uptake (3.9% injected dose/gm at 2 min after injection) and fast clearance (t1/2=24.7 min) after intravenous administration in normal mice. |
Molecular Weight | 312.34 |
Formula | C18H17FN2O2 |
CAS No. | 634911-47-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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BF-168 634911-47-0 Others BF168 BF 168 inhibitor inhibit