Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 253.00 | |
50 mg | In stock | $ 463.00 | |
100 mg | In stock | $ 682.00 | |
500 mg | In stock | $ 1,430.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 89.00 |
Description | BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model. |
Targets&IC50 | CDK8:1 nM (cell free) |
Molecular Weight | 356.42 |
Formula | C22H20N4O |
CAS No. | 2163056-91-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 120 mg/mL (336.68 mM), Sonication and heating are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BI-1347 2163056-91-3 Cell Cycle/Checkpoint CDK oral activity human NK92MI cell Inhibitor BI 1347 mouse splenic NK cell anti-tumoral activity inhibit Cyclin dependent kinase selectivity BI1347 inhibitor