Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 30.00 | |
5 mg | In stock | $ 48.00 | |
10 mg | In stock | $ 67.00 | |
25 mg | In stock | $ 88.00 | |
50 mg | In stock | $ 125.00 | |
100 mg | In stock | $ 225.00 | |
200 mg | In stock | $ 348.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 54.00 |
Description | BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB). |
In vitro | BTB06584 restores defective hemoglobin synthesis in zebrafish pinotage (pnt) mutants without evident toxicity. |
In vivo | BTB06584 inhibits F1Fo-ATPase activity in an IF1-dependent manner, does not affect ATP synthesis, and also restricts ischemia-induced damage caused by the reverse action of mitochondrial F1Fo-ATP synthase. |
Molecular Weight | 417.82 |
Formula | C19H12ClNO6S |
CAS No. | 219793-45-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 78 mg/mL (186.7 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BTB06584 219793-45-0 Endocrinology/Hormones Membrane transporter/Ion channel ATPase RAAS IF1 mitochondrial cardioprotective ATP Synthase ATPsynthase ischaemic BTB-06584 inhibit Inhibitor BTB 06584 inhibitor