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Benzydamine hydrochloride

Catalog No. T0726 CAS 132-69-4

Synonyms: Benzydamine HCl, AF864

Benzydamine hydrochloride (AF864), a locally-acting nonsteroidal anti-inflammatory drug, has local anaesthetic and analgesic properties.

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Benzydamine hydrochloride Chemical Structure

Benzydamine hydrochloride, CAS 132-69-4

Pack Size	Availability	Price/USD
50 mg	In stock	$ 33.00
100 mg	In stock	$ 47.00
200 mg	In stock	$ 60.00
500 mg	In stock	$ 95.00
1 mL * 10 mM (in DMSO)	In stock	$ 39.00

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Purity: 98.42%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Benzydamine hydrochloride (AF864), a locally-acting nonsteroidal anti-inflammatory drug, has local anaesthetic and analgesic properties.
In vivo	Benzydamine significantly lower the incidence of postoperative sore throat (POST). At 6 hours after extubation, the incidence of POST is 17.0%. Spraying benzydamine hydrochloride on the ETT cuff is a simple and effective method to reduce the incidence and severity of POST. [2]

Synonyms	Benzydamine HCl, AF864
Molecular Weight	345.87
Formula	C19H23N3O·HCl
CAS No.	132-69-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 64 mg/mL (185 mM)

Ethanol: 64 mg/mL (185 mM)

H2O: 63 mg/mL (182.1 mM)

References and Literature

1. Epstein JB, et al. Int J Radiat Oncol Biol Phys, 1989, 16(6), 1571-1575. 2. Hung NK, et al. Anesth Analg, 2010, 111(4), 882-886.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Inhibitor Library Anti-Cancer Drug Library EMA Approved Drug Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Approved Drug Library Anti-COVID-19 Compound Library Nonsteroidal Anti-Inflammatory Compound Library Anti-Cancer Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Benzydamine hydrochloride 132-69-4 Immunology/Inflammation Microbiology/Virology Neuroscience PGE Synthase COX Antibacterial inhibit AF 864 Benzydamine Hydrochloride Inhibitor Benzydamine PGE synthase Benzydamine HCl Bacterial Prostaglandin E synthase AF-864 AF864 inhibitor

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