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Benzyl benzoate

Catalog No. T0729   CAS 120-51-4
Synonyms: Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester

Benzyl benzoate (Benzoic acid benzyl ester) is one of the older preparations used for the therapy of scabies. Scabies is a skin infection caused by the Sarcoptes scabiei. Its symptoms are red spots, severe itching (particularly at night), and may lead to a secondary infection. Benzyl benzoate is useful in the therapy of scabies because it is lethal to this mite. It is also used for the therapy of lice affection of the body and head. Benzyl benzoate is not the therapy of choice for scabies because of its irritant properties.

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Benzyl benzoate Chemical Structure
Benzyl benzoate, CAS 120-51-4
Pack Size Availability Price/USD Quantity
50 mg In stock $ 33.00
100 mg In stock $ 47.00
200 mg In stock $ 66.00
500 mg In stock $ 106.00
1 mL * 10 mM (in DMSO) In stock $ 39.00
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Purity: 99.61%
Purity: 99.36%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Benzyl benzoate (Benzoic acid benzyl ester) is one of the older preparations used for the therapy of scabies. Scabies is a skin infection caused by the Sarcoptes scabiei. Its symptoms are red spots, severe itching (particularly at night), and may lead to a secondary infection. Benzyl benzoate is useful in the therapy of scabies because it is lethal to this mite. It is also used for the therapy of lice affection of the body and head. Benzyl benzoate is not the therapy of choice for scabies because of its irritant properties.
In vitro Benzyl benzoate possess oestrogenic activity in MCF7 human breast cancer cells in vitro. It is able to increase the growth of oestrogen-dependent MCF7 human breast cancer cells[1].
Cell Research Cells are added to the required volume of phenol red-free RPMI 1640 medium containing 5% DCFCS at a concentration of about 0.2 × 105 cells ml−1 and plated in monolayer in 0.5 ml aliquots into 24-well plastic tissue culture dishes (Nunc). After 24 h, the medium is changed to the same medium but containing the required concentration of test compound. Culture medium is changed routinely every 3–4 days. Cell counts are performed by counting released nuclei on a model ZBI Coulter Counter. (Only for Reference)
Synonyms Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester
Molecular Weight 212.24
Formula C14H12O2
CAS No. 120-51-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (235.58 mM)

TargetMolReferences and Literature

1. Charles AK, et al. J Appl Toxicol. 2009, 29(5):422-434.

Related compound libraries

This product is contained In the following compound libraries:
Miao medicine Compound Library Tobacco Monomer Library Drug Repurposing Compound Library Anti-Parasitic Compound Library Antiparasitic Natural Product Library FDA-Approved Drug Library Anti-infective Natural Product Library Drug-Fragment Library RO5 Drug-like Natural Product Library Human Metabolite Library

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Keywords

Benzyl benzoate 120-51-4 Microbiology/Virology Parasite Ascabiol Benzyl inhibit Inhibitor Novoscabin Scabitox Benzyl Benzoate Benzoic acid benzyl ester inhibitor

 

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