Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 production and degranulation through the suppression of cytosolic phospholipase A2 phosphorylation and phospholipase Cγ-mediated Ca2+ influx in IgE/antigen-stimulated BMMCs. OODBL also exhibits potent antitumor activity against several human cancer cell lines.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 740.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 750.00 |
Description | 1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 production and degranulation through the suppression of cytosolic phospholipase A2 phosphorylation and phospholipase Cγ-mediated Ca2+ influx in IgE/antigen-stimulated BMMCs. OODBL also exhibits potent antitumor activity against several human cancer cell lines. |
Source |
Synonyms | 1,6-O,O-Diacetylbritannilactone |
Molecular Weight | 350.41 |
Formula | C19H26O6 |
CAS No. | 1286694-67-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Britannilactone diacetate 1286694-67-4 Angiogenesis Apoptosis Chromatin/Epigenetic DNA Damage/DNA Repair Immunology/Inflammation JAK/STAT signaling MAPK Proteases/Proteasome Stem Cells JAK JNK STAT IL Receptor PARP Caspase ROS Britannilactone Diacetate Britannilactone 1,6-O,O-Diacetylbritannilactone inhibitor inhibit