Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 98.00 | |
10 mg | In stock | $ 189.00 | |
25 mg | In stock | $ 348.00 | |
50 mg | In stock | $ 589.00 | |
100 mg | In stock | $ 853.00 | |
500 mg | In stock | $ 1,690.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 113.00 |
Description | Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively. |
Targets&IC50 | CECR2:0.017 μM, BRD4:0.29 μM, BRD2:0.41 μM, BRD9:0.122 μM |
In vitro | Bromosporine (1 μM) accelerates FRAP recovery of BRD4 and CREBBP, while shows no activities against TIF1α, BAZ2A, and SMARCA2 even at 10 μM. Bromosporine (18 μM) has moderate cytotoxicity in HeLa cells. |
Molecular Weight | 404.44 |
Formula | C17H20N6O4S |
CAS No. | 1619994-69-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (135.99 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
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