Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Butoconazole Nitrate is the nitrate salt form of butoconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate (RS 35887) interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane lipid composition. This alters cell permeability and leads to growth inhibition. Butoconazole nitrate is active against many dermatophytes and yeasts. It also contains antibacterial effects against some gram-positive organisms.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 33.00 | |
100 mg | In stock | $ 47.00 | |
200 mg | In stock | $ 77.00 | |
500 mg | In stock | $ 128.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | Butoconazole Nitrate is the nitrate salt form of butoconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate (RS 35887) interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane lipid composition. This alters cell permeability and leads to growth inhibition. Butoconazole nitrate is active against many dermatophytes and yeasts. It also contains antibacterial effects against some gram-positive organisms. |
In vivo | Dexpanthenol has positive effects on protection of cerebral tissue after ischaemia reperfusion[1]. Topical application of dexpanthenol is widely used in clinical practice for the improvement of wound healing. Upregulation of IL-6, IL-1, CYP1B1, CXCL1, CCL18 and KAP 4-2 gene expression and downregulation of psorasin mRNA and protein expression are identified in samples treated topically with dexpanthenol[2]. |
Synonyms | RS 35887 |
Molecular Weight | 474.79 |
Formula | C19H18Cl3N3O3S |
CAS No. | 64872-77-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 88 mg/mL (185.3 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Butoconazole nitrate 64872-77-1 Endocrinology/Hormones Microbiology/Virology Estrogen/progestogen Receptor Antifungal Butoconazole Nitrate RS 35887 RS35887 Inhibitor Butoconazole Fungal RS-35887 inhibit inhibitor