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CALP1 acetate

Catalog No. TP1910L1 CAS TP1910L1

Synonyms: CALP1 acetate(145224-99-3 free base)

CALP1 acetate is a calmodulin (CaM) agonist (Kd of 88 µM) that binds to the CaM EF-hand/Ca2+-binding site. CALP1 blocks calcium influx and apoptosis (IC50 of 44.78 µM) by inhibiting the open of calcium channel. CALP1 blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 activates CaM-dependent phosphodiesterase activity.

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CALP1 acetate, CAS TP1910L1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 133.00
5 mg	In stock	$ 302.00
10 mg	In stock	$ 447.00
25 mg	In stock	$ 738.00
50 mg	In stock	$ 987.00
100 mg	In stock	$ 1,380.00

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Purity: 99.63%

Biological Description

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Description	CALP1 acetate is a calmodulin (CaM) agonist (Kd of 88 µM) that binds to the CaM EF-hand/Ca2+-binding site. CALP1 blocks calcium influx and apoptosis (IC50 of 44.78 µM) by inhibiting the open of calcium channel. CALP1 blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 activates CaM-dependent phosphodiesterase activity.
Targets&IC50	Calmodulin:88 µM (kd)

Synonyms	CALP1 acetate(145224-99-3 free base)
Molecular Weight	902.13
Formula	C42H79N9O12
CAS No.	TP1910L1

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. R Houtman, et al. Attenuation of very late antigen-5-mediated adhesion of bone marrow-derived mast cells to fibronectin by peptides with inverted hydropathy to EF-hands. J Immunol. 2001 Jan 15;166(2):861-7. 2. R Ten Broeke, et al. Calcium sensors as new therapeutic targets for airway hyperresponsiveness and asthma. FASEB J. 2001 Aug;15(10):1831-3. 3. M K Manion, et al. A new type of Ca(2+) channel blocker that targets Ca(2+) sensors and prevents Ca(2+)-mediated apoptosis. FASEB J. 2000 Jul;14(10):1297-306. 4. M Villain, et al. De novo design of peptides targeted to the EF hands of calmodulin. J Biol Chem. 2000 Jan 28;275(4):2676-85.

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library Kinase Inhibitor Library NO PAINS Compound Library Ion Channel Inhibitor Library

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W-9 hydrochloride A-3 hydrochloride KN-93 Calmidazolium chloride Trifluoperazine NH125 CALP2 acetate(261969-04-4 free base) Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base)

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Keywords

CALP1 acetate TP1910L1 Neuroscience CaMK CALP-1 Acetate CALP1 acetate(145224-99-3 free base) CALP 1 Acetate CALP1 Acetate CALP-1 acetate inhibitor inhibit

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