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CALP2 acetate(261969-04-4 free base)

Catalog No. TP1909L1 CAS TP1909L1

CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM. CALP2 acetate potently inhibits of adhesion and degranulation. CALP2 acetate is also a strong activator of alveolar macrophages. CALP2 acetate inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca2+ concentrations.

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CALP2 acetate(261969-04-4 free base) Chemical Structure

CALP2 acetate(261969-04-4 free base), CAS TP1909L1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 89.00
5 mg	In stock	$ 185.00
10 mg	In stock	$ 311.00
25 mg	In stock	$ 559.00
50 mg	In stock	$ 786.00
100 mg	In stock	$ 1,120.00

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Description	CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM. CALP2 acetate potently inhibits of adhesion and degranulation. CALP2 acetate is also a strong activator of alveolar macrophages. CALP2 acetate inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca2+ concentrations.
Targets&IC50	Calmodulin:7.9 µM(Kd)

Molecular Weight	1357.7
Formula	C68H104N14O13S
CAS No.	TP1909L1

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keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. R Ten Broeke, et al. Calcium sensors as new therapeutic targets for airway hyperresponsiveness and asthma. FASEB J. 2001 Aug;15(10):1831-3. 2. Robert Ten Broeke, et al. Specific modulation of calmodulin activity induces a dramatic production of superoxide by alveolar macrophages. Lab Invest. 2004 Jan;84(1):29-40. 3. M Villain, et al. De novo design of peptides targeted to the EF hands of calmodulin. J Biol Chem. 2000 Jan 28;275(4):2676-85. 4. R Houtman, et al. Attenuation of very late antigen-5-mediated adhesion of bone marrow-derived mast cells to fibronectin by peptides with inverted hydropathy to EF-hands. J Immunol. 2001 Jan 15;166(2):861-7.

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library Inhibitor Library Bioactive Compound Library Neuronal Signaling Compound Library Bioactive Compounds Library Max Metabolism Compound Library Kinase Inhibitor Library

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Keywords

CALP2 acetate(261969-04-4 free base) TP1909L1 Metabolism Neuroscience PDE CaMK CALP2 acetate(261969 04 4 free base) CALP2 acetate(261969044 free base) inhibitor inhibit

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