Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CBB1003 is a new inhibitor of histone demethylase LSD1 (IC50: 10.54 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | CBB1003 is a new inhibitor of histone demethylase LSD1 (IC50: 10.54 μM). |
In vitro | In mouse embryonic teratocarcinoma F9 cells, treatment of CBB1003 led to significant growth inhibition and the activation of CHRM4 and SCN3A expression. Treatment of mouse ES cells with CBB1003 also led to substantial inhibition of the spherical growth of ES cells [1]. CBB1003 inhibited CRC cell proliferation and colony formation. In cultured CRC cells, inhibiting LSD1 activity by CBB1003 caused a decrease in LGR5 levels while overexpression of LGR5 reduced CBB1003-induced cell death [2]. |
Molecular Weight | 521.57 |
Formula | C25H31N9O4 |
CAS No. | 1379573-88-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CBB1003 1379573-88-2 Others CBB 1003 CBB-1003 inhibitor inhibit