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CCG-100602

Catalog No. T22062 CAS 1207113-88-9

CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).

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CCG-100602, CAS 1207113-88-9

Pack Size	Availability	Price/USD
5 mg	In stock	$ 32.00
10 mg	In stock	$ 52.00
25 mg	In stock	$ 116.00
50 mg	In stock	$ 198.00
100 mg	In stock	$ 318.00
200 mg	In stock	$ 473.00
1 mL * 10 mM (in DMSO)	In stock	$ 44.00

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Purity: 99.86%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).
In vitro	CCG-100602 blocks the expression of MRTF-A/SRF-activated genes. CCG-100602 (3-30?μM) decreases the number of adherent hASC cells[1].

Molecular Weight	478.82
Formula	C21H17ClF6N2O2
CAS No.	1207113-88-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (208.85 mM), Sonification is recommended.

References and Literature

1. Laura Hyväri, et al. Myocardin-Related Transcription Factor A (MRTF-A) Regulates the Balance between Adipogenesis and Osteogenesis of Human Adipose Stem Cells. Stem Cells Int. 2020 Sep 22;2020:8853541. 2. Yoon Jeong Choi, et al. Umbilical cord/placenta-derived mesenchymal stem cells inhibit fibrogenic activation in human intestinal myofibroblasts via inhibition of myocardin-related transcription factor A. Stem Cell Res Ther. 2019 Sep 23;10(1):291.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Kinase Inhibitor Library GPCR Compound Library Inhibitor Library Anti-Cancer Metabolism Compound Library MAPK Inhibitor Library NO PAINS Compound Library HIF-1 Signaling Pathway Compound Library Neural Regeneration Compound Library Transcription Factor-Targeted Compound Library

Related Products

Related compounds with same targets

Digeranyl bisphosphonate NSC 23766 trihydrochloride Rac1 Inhibitor W56 acetate(1095179-01-3 free base) CCG-1423 ITX3 Rhosin AZA1 CCG-203971

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CCG-100602 1207113-88-9 Cell Cycle/Checkpoint GPCR/G Protein MAPK Rho Ras Inhibitor transcription inhibit serum myocardin nuclear SRF MRTF-A localization CCG100602 CCG 100602 inhibitor

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