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CCG-100602

Catalog No. T22062 CAS 1207113-88-9

Synonyms: CCG 100602, Inhibitor, transcription, inhibit, serum, myocardin, nuclear, SRF, CCG100602, MRTF-A, CCG-100602, Ras, localization

CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).

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CCG-100602, CAS 1207113-88-9

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).
In vitro	CCG-100602 blocks the expression of MRTF-A/SRF-activated genes. CCG-100602 (3-30?μM) decreases the number of adherent hASC cells[1].

Synonyms	CCG 100602, Inhibitor, transcription, inhibit, serum, myocardin, nuclear, SRF, CCG100602, MRTF-A, CCG-100602, Ras, localization
Molecular Weight	478.82
Formula	C21H17ClF6N2O2
CAS No.	1207113-88-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 100 mg/mL (208.85 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Laura Hyväri, et al. Myocardin-Related Transcription Factor A (MRTF-A) Regulates the Balance between Adipogenesis and Osteogenesis of Human Adipose Stem Cells. Stem Cells Int. 2020 Sep 22;2020:8853541. 2. Yoon Jeong Choi, et al. Umbilical cord/placenta-derived mesenchymal stem cells inhibit fibrogenic activation in human intestinal myofibroblasts via inhibition of myocardin-related transcription factor A. Stem Cell Res Ther. 2019 Sep 23;10(1):291.

Related compound libraries

This product is contained In the following compound libraries：

Cell Cycle Compound Library Bioactive Compound Library

Related Products

Related compounds with same targets

Compound 3344 AMG-510 racemate MC 976 PROTAC K-Ras Degrader-1 KRas G12C inhibitor 3 KRas G12C inhibitor 1 KRAS inhibitor-8 KRAS G12C inhibitor 17

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.