Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDDO-3P-Im is an orally active inhibitor of necroptosis with chemopreventive effects. CDDO-3P-Im can be used in studies about ischemia/reperfusion.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 96.00 | |
5 mg | In stock | $ 198.00 | |
10 mg | In stock | $ 328.00 | |
25 mg | In stock | $ 558.00 | |
50 mg | In stock | $ 788.00 | |
100 mg | In stock | $ 1,120.00 | |
500 mg | In stock | $ 2,230.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 278.00 |
Description | CDDO-3P-Im is an orally active inhibitor of necroptosis with chemopreventive effects. CDDO-3P-Im can be used in studies about ischemia/reperfusion. |
In vitro | CDDO-3P-Im (30 nM) induces differentiation of U937 cells. In RAW264.7 cells, CDDO-3P-Im suppresses NO production (IC50 = 4.3 nM)[1]. |
In vivo | CDDO-3P-Im reduces the size and the severity of the lung tumors in mouse lung cancer models. In A/J mice, CDDO-3P-Im (50-200 mg/kg; diet) decreases the number, size, and severity of tumors. CDDO-3P-Im significantly elevates heme oxygenase-1 and quinone reductase mRNA and protein levels in various mouse tissues[1]. |
Molecular Weight | 618.81 |
Formula | C39H46N4O3 |
CAS No. | 1883650-95-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225mg/mL (363.6mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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CDDO-3P-Im 1883650-95-0 Apoptosis Necroptosis CDDO 3P Im CDDO3PIm inhibitor inhibit