Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CGP71683 hydrochloride (CGP71683A) is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki <4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 68.00 | |
5 mg | In stock | $ 107.00 | |
10 mg | In stock | $ 162.00 | |
25 mg | In stock | $ 269.00 | |
50 mg | In stock | $ 393.00 | |
100 mg | In stock | $ 598.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 119.00 |
Description | CGP71683 hydrochloride (CGP71683A) is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes. |
Targets&IC50 | Y2 receptor:200 nM (Ki), Y5 receptor:1.3 nM (Ki), Y1 receptor:>4000 nM (Ki) |
In vivo | CGP71683 (1-10 mg/kg, i.p.) dose-dependently decreased nocturnal and fasting-induced food intake. CGP71683A did not have an anxiogenic-like effect in the rat social interaction test. In the open-field test, carried out immediately after the elevated plus-maze test, CGP71683A inhibited horizontal and vertical activity [2]. |
Synonyms | CGP71683A |
Molecular Weight | 512.07 |
Formula | C26H30ClN5O2S |
CAS No. | 192322-50-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 120 mg/mL (234.34 mM)
H2O: 10 mg/mL (19.53 mM)
You can also refer to dose conversion for different animals. More
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CGP71683 hydrochloride 192322-50-2 GPCR/G Protein Neuroscience Neuropeptide Y Receptor CGP71683A CGP 71683 Hydrochloride CGP 71683 NPY receptor CGP-71683 inhibit Inhibitor CGP-71683 Hydrochloride CGP71683 CGP-71683 hydrochloride CGP71683 Hydrochloride inhibitor