Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CRTh2 antagonist 3 is a powerful chemokine receptor homologous molecule expressed on Th2 cell (CRTh2) antagonists. CRTh2 antagonist 3 enhanced the activity of PDK1 on short peptide substrates with EC50 of 2 μM and Kd of 8.4 μM. CRTh2 antagonist 3 has the potential to cause cardiovascular inflammation.
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Description | CRTh2 antagonist 3 is a powerful chemokine receptor homologous molecule expressed on Th2 cell (CRTh2) antagonists. CRTh2 antagonist 3 enhanced the activity of PDK1 on short peptide substrates with EC50 of 2 μM and Kd of 8.4 μM. CRTh2 antagonist 3 has the potential to cause cardiovascular inflammation. |
Targets&IC50 | PDK1:2 μM (EC50), PDK1:8.4 μM (Ki) |
In vitro | CRTh2 antagonist 3 is a small molecule allosteric modulator of structure-based docking protein kinase PDK1. CRTh2 antagonist 3 is 5 times more potent than its parent compound. |
Molecular Weight | 356.44 |
Formula | C19H20N2O3S |
CAS No. | 312928-72-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CRTh2 antagonist 3 312928-72-6 Others CRTh-2 antagonist 3 inhibitor inhibit