Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Calcimycin (A-23187) hemicalcium salt is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). It induces Ca2+-dependent cell death by increasing intracellular calcium concentration.
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Description | Calcimycin (A-23187) hemicalcium salt is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). It induces Ca2+-dependent cell death by increasing intracellular calcium concentration. |
In vitro | Calcimycin hemicalcium salt mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner [4]. |
In vivo | Calcimycin hemicalcium salt (2.5 or 7.5 nM; intrapleural) induces protein leakage [5]. |
Synonyms | Antibiotic A-23187 hemicalcium salt, A-23187 hemicalcium salt |
Molecular Weight | 1085.322 |
Formula | C58H72CaN6O12 |
CAS No. | 59450-89-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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