Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 37.00 | |
2 mg | In stock | $ 50.00 | |
5 mg | In stock | $ 71.00 | |
10 mg | In stock | $ 107.00 | |
25 mg | In stock | $ 191.00 | |
50 mg | In stock | $ 288.00 | |
100 mg | In stock | $ 432.00 | |
500 mg | In stock | $ 987.00 |
Description | Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM). |
In vitro | Capmatinib hydrochloride blocks cell proliferation and migration or induces apoptosis in different types of cancer cells[1] |
Synonyms | INCB28060, Capmatinib hydrochloride(free base), INC280 |
Molecular Weight | 448.89 |
Formula | C23H18ClFN6O |
CAS No. | 1029714-89-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.48 mg/mL (9.99 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Capmatinib xHCl 1029714-89-3 Tyrosine Kinase/Adaptors c-Met/HGFR Apoptosis INCB28060 ATP competitive inhibit Inhibitor Capmatinib SNU-5 H441 INC 280 INC-280 Balb/c nu/nu mice Capmatinib hydrochloride(free base) U-87MG INC280 S114 INCB-28060 INCB 28060 orally active inhibitor