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Carbenoxolone disodium

Catalog No. T0992   CAS 7421-40-1
Synonyms: Biogastrone, Duogastrone, Bioral

Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, the drug is low in toxicity.

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Carbenoxolone disodium Chemical Structure
Carbenoxolone disodium, CAS 7421-40-1
Pack Size Availability Price/USD Quantity
5 mg In stock $ 32.00
10 mg In stock $ 43.00
25 mg In stock $ 66.00
50 mg In stock $ 97.00
100 mg In stock $ 166.00
500 mg In stock $ 397.00
1 mL * 10 mM (in DMSO) In stock $ 57.00
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Purity: 98.01%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, the drug is low in toxicity.
Synonyms Biogastrone, Duogastrone, Bioral
Molecular Weight 614.72
Formula C34H48Na2O7
CAS No. 7421-40-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 162.7 mM

DMSO: 37.4 mM

TargetMolReferences and Literature

1. Hausmann W, Tárnoky AL. Br J Pharmacol ChemOthers. 1966 Feb;26(2):412-20. 2. Zhang H, Wei Q, Gao Z, et al.  . G protein-coupled receptor 30 mediates meiosis resumption and gap junction communications downregulation in goat cumulus-oocyte complexes by 17β-estradio [J]. Journal of steroid biochemistry and molecular biology. 2019 Mar;187:58-67.

TargetMolCitations

1. Zhang H, Li C, Wen D, et al. Melatonin improves the quality of maternally aged oocytes by maintaining intercellular communication and antioxidant metabolite supply. Redox Biology. 2022 Feb;49:102215. doi: 10.1016 2. Zhang H, Wei Q, Gao Z, et al. G protein-coupled receptor 30 mediates meiosis resumption and gap junction communications downregulation in goat cumulus-oocyte complexes by 17β-estradio. Journal of Steroid Biochemistry and Molecular Biology. 2019, 187: 58-67

Related compound libraries

This product is contained In the following compound libraries:
Drug Repurposing Compound Library Inhibitor Library Approved Drug Library Target-Focused Phenotypic Screening Library Immunology/Inflammation Compound Library Bioactive Compounds Library Max Anti-COVID-19 Compound Library NO PAINS Compound Library Bioactive Compound Library Anti-Infection Compound Library

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Keywords

Carbenoxolone disodium 7421-40-1 Cytoskeletal Signaling Gap Junction Protein Inhibitor derivative VACV esophageal Orthopoxvirus oral ulceration Carbenoxolone peptic Biogastrone ?anticonvulsant Duogastrone inhibit muscle relaxant Vaccinia virus acid hypnotic Bioral inflammation,?cream glycyrrhetinic inhibitor

 

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