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Cetylpyridinium Chloride

Catalog No. T6439 CAS 123-03-5

Synonyms: Cetamium, Pristacin, Hexadecylpyridinium Chloride

Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.

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Cetylpyridinium Chloride Chemical Structure

Cetylpyridinium Chloride, CAS 123-03-5

Pack Size	Availability	Price/USD	Quantity
1 g	In stock	$ 30.00
1 mL * 10 mM (in DMSO)	In stock	$ 29.00

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Purity: 99.93%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
Targets&IC50	HBV capsid assembly:2.5 μM (IC50)
In vitro	Cetylpyridinium chloride (CPC) as active ingredient of antiseptic oral mouthrinses has a broad antimicrobial spectrum with a rapid bactericidal effect on gram-positive pathogens and a fungicide effect on yeasts in particular. Application of CPC at a concentration of 0.05% as a mouthrinse results in an immediate reduction in bacterial counts of 2.0 to 2.5 log steps (which is adequate to > 99%). This reverts to about 1 log step (= 90%) 1 h after application. The ability of CPC to inhibit plaque and thereby reduce gingivitis is assured. In comparison to chlorhexidine, CPC has a lower residual effect, and as a result a lesser effect against plaque and gingivitis. The efficacy of CPC against oropharyngeal candidiasis is assured. CPC mouthrinses can significantly reduce infectious aerosols in dental practice, thereby protecting both staff and the patient. The balance of intra-oral bacterial flora is not disturbed even in the case of relatively long-term use of CPC (up to six weeks). [1]
In vivo	Cetylpyridinium chloride increases the risk of severe allergic reactions, such as swelling of the mouth, face, lips or tongue, labored breathing, rashes, and hives. Ingesting high concentrations of cetylpyridinium chloride can lead to lung damage. Cetylpyridinium chloride is toxic if swallowed or inhaled. [2]

Synonyms	Cetamium, Pristacin, Hexadecylpyridinium Chloride
Molecular Weight	339.99
Formula	C21H38N·Cl
CAS No.	123-03-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 62 mg/mL (182.4 mM)

Ethanol: 63 mg/mL (185.3 mM)

DMSO: 63 mg/mL (185.3 mM)

References and Literature

1. Pitten FA, et al. Arzneimittelforschung. 2001, 51(7), 588-595. 2. Haps S, et al. Int J Dent Hyg, 2008, 6(4), 290-303.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Orally Active Compound Library Pediatric Drug Library Clinical Compound Library Approved Drug Library Anti-Bacterial Compound Library NO PAINS Compound Library Anti-Infection Compound Library Bioactive Compound Library Bioactive Compounds Library Max

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Keywords

Cetylpyridinium Chloride 123-03-5 Microbiology/Virology Others HBV Antibacterial Cetylpyridinium assembly quaternary Inhibitor anti-bacterial ammonium inhibit Cetamium mouthwashes cationic Hepatitis B virus replication Capsid pesticides Pristacin Hexadecylpyridinium Chloride Bacterial inhibitor

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