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Cinobufagin

Catalog No. T3432   CAS 470-37-1
Synonyms: Cinobufagine

Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.

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Cinobufagin Chemical Structure
Cinobufagin, CAS 470-37-1
Pack Size Availability Price/USD Quantity
1 mg In stock $ 44.00
2 mg In stock $ 63.00
5 mg In stock $ 97.00
10 mg In stock $ 147.00
25 mg In stock $ 248.00
50 mg In stock $ 369.00
100 mg In stock $ 543.00
200 mg In stock $ 776.00
500 mg In stock $ 1,160.00
1 mL * 10 mM (in DMSO) In stock $ 97.00
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Purity: 98.16%
Purity: 97.88%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.
Synonyms Cinobufagine
Molecular Weight 442.54
Formula C26H34O6
CAS No. 470-37-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 43 mg/mL (97.17 mM)

TargetMolReferences and Literature

1. Jiun-Yih Yeh, et al. Effects of bufalin and cinobufagin on the proliferation of androgen dependent and independent prostate cancer cells. The Prostate Volume 54, Issue 2, pages 112–124, 1 February 2003 2. Yu CH, et al. Apoptotic signaling in bufalin- and cinobufagin-treated androgen-dependent and -independent human prostate cancer cells. Cancer Science, 2008, 99 (12): 2467-2476 3. Peng Bei, et al. Progress in study on basic and clinical application in treating liver cancer by Cinobufagin Injection. Drug Evaluation Research, 22011-01 6. Zhang G, et al. Cinobufagin inhibits tumor growth by inducing intrinsic apoptosis through AKT signaling pathway in human nonsmall cell lung cancer cells. Oncotarget. 2016 Mar 3.

TargetMolCitations

1. Yang W, Sun X, Liu S, et al.TLR8 agonist Motolimod-induced inflammatory death for treatment of acute myeloid leukemia.Biomedicine & Pharmacotherapy.2023, 163: 114759.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Active Compound Library Chinese Pharmacopoeia Natural Product Library Traditional Chinese Medicine Monomer Library Bioactive Compounds Library Max Anti-Cancer Compound Library Target-Focused Phenotypic Screening Library Human Metabolite Library Autophagy Compound Library Ion Channel Inhibitor Library Covalent Natural Product Library

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SCH28080 Chalepensin Stauntosaponin A Blebbistatin Chebulinic acid Strictosamide Marinobufogenin Odoroside H

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Keywords

Cinobufagin 470-37-1 Apoptosis Autophagy Membrane transporter/Ion channel ATPase Inhibitor inhibit Cinobufagine inhibitor

 

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