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Clindamycin hydrochloride monohydrate

Catalog No. T22297 CAS 58207-19-5

Synonyms: Clindamycin alcoholate

Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentrations (sub-MICs). It acts by suppressing Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1), and alpha-haemolysin (Hla) production. Resistance to this compound emerges through enzymatic methylation at the antibiotic's 50S ribosomal subunit binding site (23S rRNA).

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Clindamycin hydrochloride monohydrate Chemical Structure

Clindamycin hydrochloride monohydrate, CAS 58207-19-5

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Purity: 99.59%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Clindamycin alcoholate
Molecular Weight	479.46
Formula	C18H36Cl2N2O6S
CAS No.	58207-19-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 90mg/mL (187.7mM)

References and Literature

1. Hodille E, et al. Clindamycin suppresses virulence expression in inducible clindamycin-resistant Staphylococcus aureus strains. Ann Clin Microbiol Antimicrob. 2018 Oct 20;17(1):38.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Drug Repurposing Compound Library Approved Drug Library Antibiotics Library FDA-Approved & Pharmacopeia Drug Library Bioactive Compound Library FDA-Approved Drug Library Bioactive Compounds Library Max

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Keywords

Clindamycin hydrochloride monohydrate 58207-19-5 Microbiology/Virology Antibiotic Clindamycin hydrochloride Monohydrate Clindamycin alcoholate Clindamycin Hydrochloride inhibitor inhibit

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