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Clobetasone butyrate

Catalog No. T14981   CAS 25122-57-0

Clobetasone butyrate, a synthetic glucocorticoid with topical anti-inflammatory activity, is effective in treating corticosteroid-responsive dermatoses, such as atopic dermatitis and psoriasis, especially within skin tissues.

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Clobetasone butyrate Chemical Structure
Clobetasone butyrate, CAS 25122-57-0
Pack Size Availability Price/USD Quantity
25 mg In stock $ 37.00
50 mg In stock $ 53.00
100 mg In stock $ 76.00
500 mg In stock $ 183.00
1 mL * 10 mM (in DMSO) In stock $ 50.00
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Purity: 99.35%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Clobetasone butyrate, a synthetic glucocorticoid with topical anti-inflammatory activity, is effective in treating corticosteroid-responsive dermatoses, such as atopic dermatitis and psoriasis, especially within skin tissues.
In vivo Clobetasone butyrate (application on the skin; 0.05%; 7 weeks) causes epidermal thinning in skin. Clobetasone butyrate causes much less epidermal thinning in the pig than flurandrenolone (0.05%) or fluocinolone acetonide (0.025%). Both of which causes severe atrophy[1].
Molecular Weight 478.98
Formula C26H32ClFO5
CAS No. 25122-57-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 240 mg/mL (501.06 mM)

TargetMolReferences and Literature

1. Munro DD, et al. Clobetasone butyrate, a new topical corticosteroid: clinical activity and effects on pituitary-adrenal axis function and model of epidermal atrophy. 2. Michael Stewart, et al. Clobetasone butyrate for inflammatory skin conditions.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Approved Drug Library Anti-Cancer Drug Library Drug Repurposing Compound Library Immunology/Inflammation Compound Library Bioactive Compounds Library Max Endocrinology-Hormone Compound Library ReFRAME Related Library FDA-Approved & Pharmacopeia Drug Library Bioactive Compound Library Human Metabolite Library

Related Products

Related compounds with same targets
Apararenone Nimodipine Loteprednol etabonate Clobetasol propionate LY404039 Flumethasone Mifepristone Ecdysone

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Keywords

Clobetasone butyrate 25122-57-0 Endocrinology/Hormones Glucocorticoid Receptor inhibit dermatitis psoriasis Inhibitor Clobetasone Butyrate Trimovate eczema inflammatory atopic corticosteroid skin inhibitor

 

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