Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride) is an NR2B-containing NMDA receptor antagonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 41.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 159.00 | |
25 mg | In stock | $ 322.00 | |
50 mg | In stock | $ 513.00 |
Description | Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride) is an NR2B-containing NMDA receptor antagonist. |
In vitro | Co 101244 enhances neuroprotection and reduces NMDA-evoked Ca2+?elevations effectively [1]. |
In vivo | Administration of 1 mg/kg s.c. Co 101244 displayed antidyskinetic effects with the reduction of 67% while sparing levodopa motor benefit[1]. |
Synonyms | 4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride |
Molecular Weight | 377.9 |
Formula | C21H28ClNO3 |
CAS No. | 193356-17-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 35 mg/mL (92.62mM)
DMSO: < 17.5 mg/mL (46.31mM)
You can also refer to dose conversion for different animals. More
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Co 101244 hydrochloride 193356-17-1 Neuroscience NMDAR Inhibitor Co 101244 Co-101244 Co 101244 Hydrochloride Ionotropic glutamate receptors inhibit NR2B Co101244 PD174494 iGluR PD 174494 neuroprotective PD-174494 4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride NMDA inhibitor