Powder: -20°C for 3 years | In solvent: -80°C for 1 year
3344 is an inhibitor of KRAS-effector interactions,with an affnity of 126nm.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 929.00 | |
50 mg | 6-8 weeks | $ 1,207.00 | |
100 mg | 6-8 weeks | $ 1,810.00 |
Description | 3344 is an inhibitor of KRAS-effector interactions,with an affnity of 126nm. |
In vitro | In vitro competition studies of 3344 binding to KRAS-G12V in waterLOGSY NMR show the anti-RAS scFv inhibits 3344 binding to KRAS. In view of the in vitro inhibition by the anti-RAS scFv of 3344 binding to RASand because the iDAb RAS interferes with BRET signal in cells, 3344 was used for valida?tion of the BRET2 toolbox for RAS-effector PPI inhibitors. |
Molecular Weight | 390.47 |
Formula | C24H26N2O3 |
CAS No. | 2368246-78-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Compound 3344 2368246-78-8 GPCR/G Protein MAPK Ras inhibitor inhibit