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DMNB

Catalog No. T8637 CAS 20357-25-9

Synonyms: 6-Nitroveratraldehyde

DMNB (6-Nitroveratraldehyde) is DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 15 μM, an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair in human cells.

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DMNB, CAS 20357-25-9

Pack Size	Availability	Price/USD
50 mg	In stock	$ 41.00
100 mg	In stock	$ 61.00
200 mg	In stock	$ 98.00
500 mg	In stock	$ 167.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	6-Nitroveratraldehyde
Molecular Weight	211.17
Formula	C9H9NO5
CAS No.	20357-25-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 22.5 mg/mL (106.55 mM)

References and Literature

1. Stephen D , Peter K . Vanillins--a novel family of DNA-PK inhibitors.[J]. Nuclc Acids Research, 2003(19):5501-5512.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Prostate Cancer Compound Library Anti-Pancreatic Cancer Compound Library Anti-Ovarian Cancer Compound Library Anti-Colorectal Cancer Compound Library Anti-Breast Cancer Compound Library Anti-Cancer Metabolism Compound Library Kinase Inhibitor Library NO PAINS Compound Library Glycolysis Compound Library

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

DMNB 20357-25-9 DNA Damage/DNA Repair PI3K/Akt/mTOR signaling DNA-PK precursor Inhibitor 6-Nitroveratraldehyde PET dopaminergic systems inhibit inhibitor

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